Pain at the back of the shoulder can be due to many causes, including rotator cuff tendonitis, shoulder arthritis, and referred pain from the neck. However, a rare cause of pain at the back of the shoulder is quadrilateral space syndrome. So, what is quadrilateral space syndrome, how do we diagnose it, and what do we do?

What is the Quadrilateral space? 

location of trapping of nerve in quadrilateral space syndrome

The quadrilateral space is located at the back and below the shoulder joint. It is situated between two muscles, the teres minor and the teres major. The space contains the axillary nerve and an artery, which supply the shoulder joint and muscles. Pressure in this space leads to the trapping of the Axillary nerve.

Quadrilateral space syndrome causes

Causes of trapping of the axillary nerve in the quadrilateral space include:

  • Fibrous bands or muscle swelling in the space
  • Paralabral cysts from the lower part of the labrum of the shoulder
  • Growths, such as tumours
  •  Overhead or throwing athletes. We think that repeated shoulder movement into the cocking position narrows the space.
quadilateral space syndrome anatomy

In general, this syndrome produces pain in the back of the shoulder. Often, pain occurs when moving the shoulder into the cocking position during a throw. Sometimes we can see muscle wasting or atrophy at the back of the shoulder. Also, people can report pins and needles or numbness in the upper arm.

When examining a shoulder, we often find point tenderness in the quadrilateral space and weakness and wasting of the deltoid and the muscles behind the shoulder. 

Other causes of shoulder muscle atrophy

Not all shoulder muscle atrophy is due to quadrilateral space syndrome. In general, other common causes of shoulder pain and muscle atrophy include brachial neuritis, suprascapular nerve compression at the back of the shoulder, thoracic outlet obstruction, and neck nerve compression.

Quadrilateral space syndrome radiology

paralabral cyst shoulder on MRI

Often, an MRI scan of the shoulder is the most helpful investigation. Often, we see swelling and wasting of the teres minor muscle. Sometimes, paralabral cysts from the inferior labrum are seen compressing the space.

Finally, in complex cases where the diagnosis is uncertain, we think a diagnostic local anaesthetic block can be helpful to confirm a diagnosis.

Quadrilateral space syndrome treatment

In general, treatment depends on the cause of the trapping.

Firstly, in mild cases with a normal MRI, physical therapy can improve pain and function after a few months. Sometimes an ultrasound-guided cortisone injection can be directed next to the axillary nerve. Also, we can aspirate a paralabral cyst to reduce pressure on the nerve.

Finally, for more severe symptoms or cases due to an apparent compression (such as a paralabral cyst), surgical decompression and labrum repair are needed.

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